TY - JOURS T1 - Chronobiologische Aspekte der Schmerzempfindung GUTENBRUNNER, CHRISTOPH JAS - Jahr für Goethe. JF - Jahrbuch für Goetheanismus PY - 2004 VL - 2004 SP - 23 EP - 46 DO - 10.18756/jfg.2004.23 SN - Print :1866-4830 Online : 2750-2341 LA - de N2 - N1 - Chronobiological aspects of pain sensationIt has been known for a long time that sensation of pain shows large variations The first systematic investigations were carried out at the beginning of the 20th century Principally pain intensity can be influenced by sensitivity changes of the nociceptors in peripheral tissue and by processing of the pain signal in the central nervous system Furthermore it is known that different qualities of pain such as the socalled surface pain 1st pain AB fibres and internal pain 2ud pain C fibres are related to different afferences and are subjectcd to different intensity changes Finally changes of pain sensation are to be expected depending on variations in the paincausing diseaseMore recently circadian changes of pain sensation have been well investigated whereas maximum sensation of protopathic pain is at night for epicritic pain it is during daytime Clinical observations are available for example for headache and pectanginous pain The effectiveness of analgesics and the use of analgesic placebos show clear circadian influences Moreover ultra and infradian variations of pain sensation are observed Infradian pain sensation variations are mostly related to the menstrual cycle to reactive periods of several days and to influences of the annual rhythmnbsp AB - ST - Chronobiologische Aspekte der Schmerzempfindung UR - https://dx.doi.org/10.18756/jfg.2004.23 Y2 - 2024-05-18 05:51:10 ER -