TY - JOURS T1 - Jahresrhythmus und Schilddrüsenfunktion unter besonderer Berücksichtigung des Morbus Basedow HECKMANN, CHRISTIAN JAS - Jahr für Goethe. JF - Jahrbuch für Goetheanismus PY - 2004 VL - 2004 SP - 9 EP - 22 DO - 10.18756/jfg.2004.9 SN - Print :1866-4830 Online : 2750-2341 LA - de N2 - N1 - Annual rhythm and thyroid function with particular reference to Graves diseaseTurning points in the biological year are not identical to those of the cosmicgeophysical year The ascending half of the biological year February to August is marked by an ergotropic tendency for vegetatively autonomous regulation Correspondingly in the descending half of the year August to February a trophotropic condition is predominantThe thyroid gland an endocrine organ of great importance for heat production shows functional and structural annual variations Both its hormone production and volume are lower in summer than in winterSome aspects of autoimmune hyperthyroidism Graves disease also depend on the season The illness is diagnosed more frequently in summer than in winter although the interval between the start of the illness onset of symptoms and establishing that disease is present time of diagnosis can on average be up to three months This latency time in particular shows marked seasonal variations being appreciably shorter in summer than in winter Taking into consideration the onset of symptoms autoimmune hyperthyroidism shows an annual rhythm with two peaks corresponding to maxima in April and October In the geophysical year these times are when the outside temperature is changing most rapidlyThe course of Graves disease hyperthyroidism occurs in waves or phases such that a phase of illness usually lasts from twelve to eighteenmonths Regarding the matter of the danger of a rccurrence there is evidence that a trial suspension of thyrostatic therapy is associated with a lower risk of recurrence in the summer months The significance of possible influencing factors for a rccurrcncc raiscd thyroid volume raised TSHreceptorAb were examined in comparison with the time of year of trial suspension of therapy This showed that considerable significance should be attached to the annual cycleTherefore in thyroid disease there are chronophysiological chronopathological and chronotherapeutic aspectsnbsp AB - ST - Jahresrhythmus und Schilddrüsenfunktion unter besonderer Berücksichtigung des Morbus Basedow UR - https://dx.doi.org/10.18756/jfg.2004.9 Y2 - 2024-04-30 03:09:14 ER -