TY - JOURS
T1 - Lebendige Mineralwelt im Knochen 
Gehlig, Roselies
JAS - Jahr für Goethe.
JF - Jahrbuch für Goetheanismus
PY - 2008
VL - 2008
SP - 145
EP - 194
DO - 10.18756/jfg.2008.145
SN - Print :1866-4830 Online : 2750-2341 
LA - de
N2 - 
N1 - The mineral realm in living boneThe mineralisation of the skeleton is based on the dissolved calcium phosphate and carbonate of body fluids and even on the water and carbon dioxide of the earths hydrosphere and atmosphere But it is also related to the mineral realms crystalline calcium phosphate and carbonate especially to apatite The polar extremes of skeleton formation actually lie in the environment which expresses itself in a distinct tendency to twodimensionality First of all organicmineral germs arise on and in the outer membranes of the mitochondria of cartilage and bone cells and the outer membranes of extracellular vesicles Apatite precursors brushite octacalcium phosphatelike phases form lamellar structures in close relation to the aqueous realm Collagen fibres gradually become completely coated with biological apatite Despite its three dimensional networked stable scaffoldingstructure the biological apatite remains connected With twodimensionality Its microcrystallinity provides the skeleton with an enormous inner surface area which is in intense exchange with the environment via the hydrate envelopes of the crystallite Nonapatite areas of the surface of the apatite crystallite contain highly reactive exehangeable labile phosphate and labile carbonate which is greatest in the cartilaginous and young bone mineral Labile carbonate is physiologically decisive for thisAs the skeleton matures stable phosphate and stable carbonate increase Above all stable carbonate replaces stable phosphate the most stable position in the crystal structure To a lesser extent it is replaced by the more readily exchangeable hydroxide fluoride or chloride The latter and the equally exchangeable calcium are localised in particular migration zones of the crystal structureThe extent of variation and readiness to partake in processes of apatite are particularly strongly connected with carbonate Even in the mineral realm apatite shows an extraordinary capacity for absorption various exogenous ions Apatites natural typical structural variability makes it particularly suited to its function in the organism But even the carbonate of the mineral realm is very inclined to variation between on the one hand totally dissolved calcium hydrogen carbonate and on the other hand calcite the mineral with the greatest number of formsSomething of the nature of bone already resides in the apatite of the mineral realm No mineral other than apatite can form the skeleton in such a living way and keep it in connection with life
AB - 
ST - Lebendige Mineralwelt im Knochen 
UR - https://dx.doi.org/10.18756/jfg.2008.145
Y2 - 2024-04-29 01:22:39
ER -